Molecular Formula | C20H23N3O |
Molar Mass | 321.42 |
Density | 1.12±0.1 g/cm3(Predicted) |
Boling Point | 512.4±52.0 °C(Predicted) |
pKa | 10.10±0.35(Predicted) |
Storage Condition | 2-8°C(protect from light) |
biological activity | CM10 is an effective selective inhibitor of aldehyde dehydrogenase 1A family (ALDH1A). for ALDH1A1, the IC50 values of ALDH1A2 and ALDH1A3 are 1700 nM,740 nM and 640 nM respectively. CM10 has anticancer activity. | |||
target | TargetValue ALDH1A3 640 nM ALDH1A2 740 nM ALDH1A2 740 nM ALDH1A1 1700 nM | |||
Target | Value | |||
ALDH1A3 (Cell-free assay) | 640 nM | |||
ALDH1A2 (Cell-free assay) | 740 nM 740 nM | |||
ALDH1A1 (Cell-free assay) | 1700 nM |